Newpharmablog. Health News

There are three main medicines in this group. Detailed below are their recommended doses and their interactions with other medicines.Nevirapine: Two hundred milligrams of this medicine is recommended four times a day for the first fourteen days followed by the same dose twice a day. Common side-effects include rash, hepatitis and increased levels of an enzyme called transaminase. Nevirapine interacts with oral contraceptives, some medicines used for treatment of tuberculosis (such as rifampicin), protease inhibitors (recommended for treatment of HIV infection) and triazolam (used for management of sleep disorders including sleeplessness).Delavirdine: The recommended dose of this medicine is four hundred milligrams three times a day. Common side-effects  include   rashes  and headache. Delavirdine is not recommended with tranquillisers or some medicines used for management of sleep disorders (such as alprazolam, triazolam, midazolam, etc.) medicines used for epilepsy (such as phenytoin, carbamazepine and phenobarbitol), cisapride (a medicine used for management of vomiting, increased acids in the stomach) and amphetamines.Delavirdine increases the level of some medicine such as dapsone (recommended for management of leprosy), clarithromycin (antibiotic), quinidine (used for treatment of malaria) and protease inhibitors such as indinavir and saquinavir (used for management of HIV infection).Antacids can interact with delavirdine and therefore a gap of about one hour is recommended between taking these two medicines.Efavirenz: The recommended dose is six hundred milligrams four times a day. Common side-effects include rash, dizziness, sleeplessness, abnormal dreams, confusion, lack of concentration, loss of memory, hallucinations, etc. Efavirenz interacts with medicines such as cisapride, midazolam, triazolam, etc., and is therefore not recommended with them. It also decreases the levels of two protease inhibitors including indinavir and saquinavir and increases the level of two other protease inhibitors including nelfinavir and ritonavir. Efavirenze can interact with some medicines such as rifampicin, pheynytoin, etc., and is therefore recommended only under direct supervision by a medical practitioner.*21\288\2*

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. This entry was posted on Friday, May 20th, 2011 at 4:17 am and is filed under HIV. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.